フラノクマリン含有食品一覧

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はじめに

Furanocoumarins are naturally occurring chemical compounds in certain foods, including various citrus fruits such as Grapefruit, which are known for their interaction with medications.
These compounds can interfere with the metabolism of certain drugs in the body, particularly affecting the enzyme CYP3A4, which could potentially lead to increased medication levels and side effects.
Foods that notably contain high levels of furanocoumarins include grapefruit, sweetie, and pomelo.
Lemons and oranges are considered to have lower furanocoumarin levels, reducing the risk of adverse reactions with medications.
It is advisable for individuals on certain medications to avoid consuming these foods or seek medical advice before intake.

Grapefruit: Known for its high furanocoumarin content, particularly in its juice.
Sweetie: Shares similar levels of furanocoumarins as grapefruit, making it a concern.
Pomelo: Another citrus fruit with considerable furanocoumarin levels.
Limes and Lemons: Known to have some furanocoumarin, but generally lower than grapefruit.
Seville Orange: Often used in marmalades, and contains notable furanocoumarins.

Furanocoumarins can affect drug metabolism leading to increased blood levels of certain medications.
Such interactions could heighten side effects, particularly when paired with drugs like Calcium Channel Blockers or Immunosuppressants.
Avoiding high-furanocoumarin foods can be crucial for individuals on these medications.
Those consuming these foods may experience unexpected health implications due to increased medication absorption.
It is important to monitor Dietary Intake if under medical treatment.

Furanocoumarins primarily affect drugs metabolized by the CYP3A4 enzyme.
Notable drugs include Statins, calcium channel blockers, and immunosuppressants.
Ingesting foods rich in furanocoumarins can significantly increase drug levels.
The interaction can last for several days after consumption of these foods.
Caution is advised when consuming these foods with relevant drug prescriptions.

Consult with healthcare providers before consuming furanocoumarin-rich foods if on medication.
Check labels on processed and packaged foods for citrus-derived ingredients.
Florida or Seville oranges should be consumed with caution due to potential high levels.
Inform healthcare providers of any unexpected side effects experienced.
Consider safer alternative citrus options if a preference for citrus remains.